Burnie Burns, born as Michael Justin Burns, is the CEO of RoosterTeeth and the creator of Red v. Blue and Lazer Team, along with other projects created under RoosterTeeth. Burnie was born in New York, but has lived most of his life in Austin, Texas, where RoosterTeeth is currently located.
In his early life, he went to Alief Elsik High School, where he got the nickname “Burnie.” It was given to him by a classmate who wanted to differentiate him between the other Michael’s in his class. He then went on to go to The University of Texas at Austin. Here, he started working on the campus TV station. While he was there, he started a new TV program Sneak Peak, which is the longest running student television show at The University of Texas at Austin.
While attending school, he was working at a tech company where he met future co-founders of RoosterTeeth, Geoff Ramsey and Gus Sorola. As they started working together, they started to develop a new, game changing video-game based videos. The videos were called Red v. Blue. They used a technique called machinima, which means to take pre-recorded game play from a video game and dub audio over top to make create a story. When they first used this technique, it was widely disregarded, and nobody really paid any attention to the series. After they got recognition from Computer Gaming World, the series became so popular, that they had to revise their original thought of only making these short, comedic videos to a full season length, consisting of 20 episodes or so per season.
Because of the popularity they were getting, the decided to make their own website, properly named redvblue.com. Their domain name has since changed to RoosterTeeth.com, because after Red v. Blue, their company grew beyond their imaginations. Over the course of the next couple of years, they went on to make more machinima content, like The Strangerhood and PANICS. These shows made their popularity grow even more, so Burnie had to grow his company.
Presently, they have made a lot of great content. To name some, Immersion, where they take video game situations and try to replicate them in real life, RWBY, being a very popular anime show, and The RoosterTeeth Podcast, where his co-founder, Gus Sorola, hosts a podcast every week and has guests through out the company talk about recent events and popular topics.
Because of them, they have inspired me to pursue the Communication Media field so i can one day hopefully work for them. To hear their story, to have them come up from nothing and create such a successful company, who has produced a Blockbuster movie called Lazer Team, it has motivated me to learn all i can about production and editing.
Have you ever heard of these guys? Do you love them as much as i do? Let me know in the comments below about what you think!
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In mucous membrane pemphigoid, treatment was directed to the sites involved and managed with systemic corticosteroids and immunosuppressants/biologics. There was no universal consensus on the first-line treatment for epidermolysis bullosa acquisita, but a combination of immunosuppressive, anti-inflammatory, and anti-neutrophil therapy was utilized. Comparison of the management guidelines revealed underrepr
Entinostat
We aimed to determine the diagnostic and prognostic value of serum irisin level in patients with acute pulmonary embolism (PE) admitted to the emergency department.
Ninety patients who underwent computed tomography pulmonary angiography (CTPA) due to suspected PE were included in the study. Demographic data, PE risk factors, and associated diseases, vital signs, Wells score, Revised
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In today’s hectic world, time management is critical for personal and professional success. Whether you’re a student, a businessperson, or someone balancing multiple commitments, the ability to strategically manage your time serves as a foundation to accomplishing your goals. In this detailed guide, you’ll uncover actionable strate
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OBJECTIVE Utilization of nonpharmacological pain management may prevent unnecessary use of opioids. Our objective was to evaluate the impact of chiropractic utilization upon use of prescription opioids among patients with spinal pain. DESIGN AND SETTING We employed a retrospective cohort design for analysis of health claims data from three contiguous states for the years 2012-2017. SUBJECTS We included adults
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In today’s rapidly evolving digital world, online shopping has become an essential part of our daily routines. With the expansion of e-commerce platforms, understanding how to enhance your online shopping adventure is more important than ever. This article explores various ways you can enhance your e-commerce experience to benefit you.
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Based on the collected observations, it seems too early to promote disulfiram as a promising new treatment until the reasons underlying the reported toxicities have been explored, and the results of a well-conducted double blind clinical trial published. The importance of taking into account patient-reported outcomes in Lyme Disease is underlined by the present study. Copyright © 2020 Trautmann, Gascan and Ghozzi.D
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Aim The influence of surgical margin on the prognosis of patients with early solitary hepatocellular carcinoma (HCC) (≤5 cm) is undetermined. Methods The data of 904 patients with early solitary HCC who underwent liver resection were collected for recurrence-free survival (RFS) and overall survival (OS). Propensity score matching (PSM) was performed to balance the potential bias. Results Log-rank tests showed that 2 mm w
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The concept of a so-called urban advantage in health ignores the possibility of heterogeneity in health outcomes across cities. Using a harmonized dataset from the SALURBAL project, we describe variability and predictors of life expectancy and proportionate mortality in 363 cities across nine Latin American countries. Life expectancy differed substantially across cities within the same country. Cause-specific mortal
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However, subgroup analyses demonstrated that there were no significant differences in all complication if the studies had matched controls and regardless of data source (database or nondatabase studies). The revision rates were similar between both groups at a 12-24months follow-up. Two studies reported a significant reduction in costs in favour of outpatient TSA.
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There were 133 amputations in CREDENCE (3·0% annual event rate) and 187 amputations in CANVAS (1·8% annual event rate), with prior amputation being the strongest predictor of future amputation in both groups. Effects of canagliflozin on amputation risk were significantly different between trials (pheterogeneity 0·02, I2 =82%), but this was not explained by participant or trial differences. There was no
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We propose an automated method for the segmentation of lumen intima layer of the common carotid artery in longitudinal mode ultrasound images. The method is hybrid, in the sense that a coarse segmentation is first achieved by optimizing a locally defined contrast function of an active oblong considering its five degrees-of-freedom, and subsequently the fine segmentation and delineation of the carotid arter
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In previous studies, we produced changes in gene expression in the brain of mice by early postnatal administration of valproic acid (VPA), with distinct differences between genders. The addition of S-adenosine methionine (SAMe) normalized the expression of most genes in both genders, while SAMe alone induced no changes. We treated pregnant dams with a single injection of VPA on day 12.5 of gestation, or with SAMe
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From baseline to follow-up, the PROMIS measures showed a reduction in depression (P=.02), pain interference (P=.003), and average pain impact score (P=.007). Pain self-efficacy increased ((P less then .001), whereas opioid use had a 13% reduction (P=.03). CONCLUSIONS The eHealth chronic pain management platform, OWLCP, is a potential tool to reduce the impact of chronic pain for low-income racially diverse popu
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327). The Kaplan-Meyer Survival analysis was performed, and there were no differences between the groups before 31.5 weeks. Logistic regression showed that a previous PB (< 37 weeks) presented an odds ratio (OR) of 15.951 (95% confidence interval [95%CI] 1.294-196.557;
= 0.031*) for PB < 34 weeks in the PPG.
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Finally, cerebral infarct size assessment and TUNEL staining confirmed that overexpression of miR-484 alleviated cerebral ischemia/reperfusion injury in mice, and overexpression of BCL2L13 could abolish the effect of miR-484-suppressed cell apoptosis. All these results suggested that miR-484 alleviates cerebral ischemia/reperfusion injury-induced neuronal apoptosis in mice by targeting apoptosis facilitator BCL2L1
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As a result, the modified catalysts enhance the whole oxidation process with favorable formation of epoxide product at low reaction temperatures ( less then 225 °C). Our findings highlight the impact of surface chemically bound polydimethylsiloxane (PDMS) upon tailoring the surroundings of the catalyst surface, and that combined with facet-effect of s
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Allografts were fresh in 4 studies, demineralized in 2 studies, and freeze-dried after sterilization in 1 study. All scores performed in the different studies increased between pre-operative and post-operative evaluations (mean + 36.8 points for the ASES). Global rate of recurrence was 3.9% (11 patients) (0-11%), comprising 6 cases of dislocation (2.1%) and 5 subluxations (1.8%). Allograft healing occurred in 93.5
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G. lucidum might have aided in restoring the memory and learning abilities of the AD model animals through maintaining neuronal structure and function. Thus, G. lucidum could be suggested as a medicotherapeutic agent against AD.Black truffle mushroom, Tuber melanosporum, is effective in treating various symptoms associated with diabetes mellitus such as hyperglycemia, oxidative stress, and hyperlipidemia and is used
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5- and 1-fold, respectively. Intermediates of the tricarboxylic acid cycle (TCA), stress-related metabolites, vitamin B5, and several flavonoids were significantly more abundant in PGW. Most lipids were also significantly higher in grafted watermelon. This is the first report providing a comprehensive picture of watermelon metabolic profile and changes induced by grafting. Hence, the untargeted high-throughput L
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비아그라는 남성의 발기부전 치료에 널리 사용되는 약물로, 많은 사람들이 이 약물을 통해 삶의 질을 향상시키고 있습니다. 그러나 비아그라에 대한 정보는 많지만, 실제로 구매하고 사용하는 과정에서 혼란을 느끼는 분들이 많습니다. 이 가이드는 비아그라의 가격, 구매 사이트, 그리고 처방전 없이도 사용할 수 있는 옵션에 대해 자세히 설명하여 여러분이 필요로 하는 정보를 제공합니다.
비아그라를 처음 사용하시는 분들부터 이미 경험이 있는 분들까지, 올바른 정보를 통해 비아그라를 쉽게 접근하고 구입할 수 있도록 돕고자 합니다. 비아그라 구매에 관한 주요 사항들을 알아보고, 추천하는 구매 사이
비아그라 구입
비아그라는 남성의 성기능 개선을 위해 널리 사용되는 약물로, 많은 남성들이 성생활의 질을 높이기 위해 찾고 있는 제품입니다. 하지만 비아그라에 대한 정보가 부족한 경우, 어떻게 구매해야 할지, 처방전이 필요한지 여부에 대해 고민할 수 있습니다. 이 글에서는 비아그라의 기본 정보부터 시작해, 구매 방법, 가격, 그리고 처방전 없이 구입하는 방법까지 자세히 안내드리겠습니다.
비아그라 구매에 대한 궁금증을 해소하고, 안전하고 효과적인 방법으로 비아그라를 구입할 수 있는 팁을 제공하는 것이 이 글의 목적입니다. 비아그라 구입을 고려하고 있는 독자 여러분께 유용한
Selleckchem ON-01910
A major challenge in the ICU is optimization of antibiotic use. This review assesses current understanding of core best practices supporting and promoting astute antibiotic decision-making.
Limiting exposure to the shortest effective duration is the cornerstone of antibiotic decision-making. The decision to initiate antibiotics should include assessment of risk for resis
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Artificial intelligence (AI) has become a pillar of technological advancement in the modern world. As it saturates various sectors, AI shows its power to transform industries ranging from healthcare to finance. Understanding its importance is key in embracing a ever-evolving technological landscape.
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Despite recent groundbreaking advances in the treatment of cutaneous melanoma, it remains one of the most treatment-resistant malignancies. Due to resistance to conventional chemotherapy, the therapeutic focus has shifted away from aiming at melanoma genome stability in favor of molecularly targeted therapies. Inhibitors of the RAS/RAF/MEK/ERK (MAPK) pathway significantly slow disease progression. However, long-term c
Solcitinib
Trypsin is the protease of choice in bottom-up proteomics. However, its application can be limited by the amino acid composition of target proteins and the pH of the digestion solution. In this study we characterize ProAlanase, a protease from the fungus Aspergillus niger that cleaves primarily on the C-terminal side of proline and alanine residues. ProAlanase achieves high proteolytic activity and specificity when di
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In non-habitual situations, cognitive control aligns actions with both short- and long-term goals. The capacity for cognitive control is tightly tied to the prefrontal cortex, whose expansion in humans relative to other species is thought to support our superior cognitive control. However, the posterolateral cerebellum has also expanded greatly relative to non-human primates and has an organizational st
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Psychologists are experts in the human mind. They have graduated from a doctoral program in clinical psychology or counseling and work directly with customers.
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Based on the loss-of-function experiments, silencing
expression significantly inhibited malignancy progression. In terms of the mechanism,
acted on the
(
) by direct binding, which promoted BC cell growth. Furthermore, in the promoters of
, the trimethylation of
could be regul
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Thank you for the opportunity to respond to the issues raised by Ferrés-Padró et al. in their recent letter to the editor […].Microstructural phase evolution during melting and casting depends on the rate of cooling, the collective mobility of constituent elements, and binary constituent pairs. Parameters used in mechanical alloying and spark plasma sintering, the initial structure of binary alloy pairs, are some of the factors that
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Many patients suffering from mental health issues, such as anxiety and depression receive care through a primary health care provider (PCP). Some PCPs have innovative approaches to tackle this issue by collaborating with behavioral care managers and eConsults.
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Most of isolates had been discovered to be active. Moreover, 1-5 inhibited melanin production in B16-F10 mouse melanoma cells, without showing any cytotoxicity. Beside ginsenoside Rd (6) and ginsenoside Rg3 (8) in PPD and notoginsenoside R1 (12) in PPT-type saponins, 1 ended up being probably the most powerful melanogenesis inhibitory task. In this paper, we high
Reversan
It is concluded that the data from two different pharmaceutical formulations is supported by the same calibration curve, which indicates that optical porosimetry is a general technique for pharmaceutical materials that does not require frequent calibrations.The nucleus accumbens (NAc) is critical for regulating the appetitive and consummatory phases of motivated behavior. These experiments examined the effects of dopamine
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Posttranslational modifications, such as phosphorylation, are a powerful means by which the activity and function of nuclear receptors such as LXRα can be altered. However, despite the established importance of nuclear receptors in maintaining metabolic homeostasis, our understanding of how phosphorylation affects metabolic diseases is limited. The physiological consequences of LXRα phosphorylation have, until re
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In addition, we experimentally clarified the effect of the number and position of teacher labels on performance.
Compared with supervised learning when a small number of labeled data was obtained, the performance of the proposed method was shown to be superior.
Our 4S leverages a limited number of labeled data and a large amoun
SHP099
INTRODUCTION ‘Systems thinking’ is often recommended in healthcare to support quality and safety activities but a shared understanding of this concept and purposeful guidance on its application are limited. Healthcare systems have been described as complex where human adaptation to localised circumstances is often necessary to achieve success. Principles for managing and improving system safety developed by th
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Herein, we summarize the various hallmark molecular traits of cancers that are reported to be regulated by the TTP family RBPs. We emphasize the role of the TTP family RBPs in the regulation of trait-associated mRNA targets in relevant cancer types/cell lines. Finally, we highlight the potential of the TTP family RBPs as prognostic indicators and discuss the possibility of targeting these TTP family
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Colpocleisis just as one obliterative surgery with regard to pelvic wood prolapse: is it still a viable option in the twenty-first century? Story evaluation.
In addition, enhanced levels of BDNF and histone H4 acetylation were found after the intervention. Grape juice consumption did not potentiate these effects, since any significant differences between the AQ and AQ+GJ groups were not found in a
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Mechanical thrombectomy is now the standard of care for acute ischemic stroke patients with large vessel occlusions, and can be performed with several devices and techniques. One of these techniques, direct aspiration (DA), consists of navigating a large-bore catheter up to the face of the clot and initiating forceful suction. This comprehensive review has three objectives (1) to describe the direct aspiration tech
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To be able to treat irreducible unilateral vertically displaced pelvic ring disruption (UVDPRD) using closed reduction, we introduced a technique named Unlocking Closed Reduction Technique (UCRT) and evaluated its effectiveness with improved pelvic closed reduction system (PCRS).
A retrospective study was performed in our department. Between January 2014 and December 2017, 43 patient
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Interns retained all skills and improved upon techniques frequently practiced during intern year.
An eight-week boot-camp effectively improved technical skills among surgery interns. Interns retained all skills and improved upon techniques frequently practiced during intern year.
Our objective was to examine the influence of silence on team action in the operating room.
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OBJECTIVES Spit masks are used by law enforcement officers and healthcare providers to protect themselves from the spread of communicable disease by subjects who pose a potential risk of biological exposure by spitting. Little research is available regarding the safety of these masks. However, concerns surround the ability of subjects to properly ventilate while wearing these masks as there are several a
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Although physiological levels of iron are essential for numerous biological processes, excess iron causes critical tissue injury. Under iron overload conditions, non-chelated iron generates reactive oxygen species that mediate iron-induced tissue injury with subsequent induction of apoptosis, necrosis, and inflammatory responses. Because liver is a central player in iron metabolism and storage, it is vulnera
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The purpose of this study was to assess the feasibility of dual-energy CT-based material decomposition using dual-X-ray spectra information to determine local concentrations of holmium microspheres in phantoms and in an animal model.
A spectral calibration phantom with a solution containing 10 mg/mL holmium and various tube settings was scanned using a third-generation dual-energy CT
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Double ipsilateral femoral fractures account for 1-9% of femoral fractures. There is no clear advantage between single or double implant osteosynthesis. We present a series of patients with double ipsilateral femoral fractures, to address the challenges in treatment, namely the implants for osteosynthesis and complications of treatment.
We retrospectively studied 16 patients (
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2%), offering ideas for activities to distract users from self-harming. Other techniques that were used often were “Social Support (unspecified)” (27.0%) and “Behavior Substitution” (10.6%). This study provides the first analysis of BCTs present in mental health apps which are designed to target the reduction of self-harm in young people. Future research is needed to evaluate the effectiveness o
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Then, a classifier ensemble was created and updated over time to account for changes in streaming input data distribution wherein new classifiers are added to the ensemble in accordance with estimated shifts. Furthermore, using two publicly available BCI-related EEG datasets, the proposed method was extensively compared with the state-of-the-art single-classifier based passive scheme, single-classifier based active sch