Burnie Burns, born as Michael Justin Burns, is the CEO of RoosterTeeth and the creator of Red v. Blue and Lazer Team, along with other projects created under RoosterTeeth. Burnie was born in New York, but has lived most of his life in Austin, Texas, where RoosterTeeth is currently located.
In his early life, he went to Alief Elsik High School, where he got the nickname “Burnie.” It was given to him by a classmate who wanted to differentiate him between the other Michael’s in his class. He then went on to go to The University of Texas at Austin. Here, he started working on the campus TV station. While he was there, he started a new TV program Sneak Peak, which is the longest running student television show at The University of Texas at Austin.
While attending school, he was working at a tech company where he met future co-founders of RoosterTeeth, Geoff Ramsey and Gus Sorola. As they started working together, they started to develop a new, game changing video-game based videos. The videos were called Red v. Blue. They used a technique called machinima, which means to take pre-recorded game play from a video game and dub audio over top to make create a story. When they first used this technique, it was widely disregarded, and nobody really paid any attention to the series. After they got recognition from Computer Gaming World, the series became so popular, that they had to revise their original thought of only making these short, comedic videos to a full season length, consisting of 20 episodes or so per season.
Because of the popularity they were getting, the decided to make their own website, properly named redvblue.com. Their domain name has since changed to RoosterTeeth.com, because after Red v. Blue, their company grew beyond their imaginations. Over the course of the next couple of years, they went on to make more machinima content, like The Strangerhood and PANICS. These shows made their popularity grow even more, so Burnie had to grow his company.
Presently, they have made a lot of great content. To name some, Immersion, where they take video game situations and try to replicate them in real life, RWBY, being a very popular anime show, and The RoosterTeeth Podcast, where his co-founder, Gus Sorola, hosts a podcast every week and has guests through out the company talk about recent events and popular topics.
Because of them, they have inspired me to pursue the Communication Media field so i can one day hopefully work for them. To hear their story, to have them come up from nothing and create such a successful company, who has produced a Blockbuster movie called Lazer Team, it has motivated me to learn all i can about production and editing.
Have you ever heard of these guys? Do you love them as much as i do? Let me know in the comments below about what you think!
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Child participation in type 1 diabetes (T1D) self-care is needed in developing countries due to a lack of resources, especially during the school day. This pilot study evaluated the feasibility of a therapeutic play intervention (ITP) versus standard education (SE)on the ability of children with T1D to correctly perform insulin injection technique.
Children with T1D (7-12
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MYH9 was identified as the target downstream gene of miR-124-3p. A series of experiments were used to confirm the miR-124-3p/MYH9 axis. Finally, it was found that PI3K/AKT/NF-κB signaling cascades may be involved in the modulation of microglia by exosomal miR-124-3p.
A combination of miRNAs and neuron-derived exosomes may be a promising, minimally invasive approach for the treatment
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d the associated electron density maps are needed. These new methods are available as a well-documented Python package on GitHub and the Python Package Index under a modified Clear BSD open source license.Eating disorder is highly associated with obesity and it is related to brain dysfunction as well. Still, the functional substrates of the brain associated with behavioral traits of eating disorder are underexplored. Ex
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Oral lichen planus (OLP) is an immune-mediated disease of the oral mucosa with idiopathic aetiology. It is frequently treated with topical corticosteroids (applied as gels, mouthwashes, or sprays); however, the mucosal exposure times of topical corticosteroids are short because of removal by the constant flow of saliva and mechanical forces. In this study we used cell monolayers, as well as oral
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Volatile organic compounds (VOCs) are important precursors of ozone and particulate matter; thus, their impacts on air quality are particularly significant. To study the composition characteristics and sources of VOCs in Lianyungang City, four national control sites were selected to conduct VOCs sampling and analysis on typical days in spring, summer, and autumn. Concentrations of VOCs, the effects of different compon
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The majority of psoriatic arthritis (PsA) patients present at dermatology clinics with cutaneous psoriasis up to 10 years prior to arthritis onset; therefore, applying a suitable screening tool to detect PsA early is essential for dermatologists. This study aimed to validate and evaluate the Persian version of two PsA screening questionnaires, the early arthritis for psoriatic patients questionnaire (EARP) and the psori
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1%, p= 0.23). No primary graft failure occurred in the group of precut grafts.
Both methods lead to comparable results for visual acuity, corneal deswelling, endothelial cell density, and re-bubbling rate. A previously described higher graft failure rate for precut tissues could not be confirmed in our study. Thus, we do not see medical reasons against the use of precu
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Low-tech active learning (AL) exercises in face-to-face (F2F) undergraduate biomechanics courses improve student learning vs. lecture alone. This study compared learning of biomechanics concepts with AL implemented in two course formats (hybrid HB vs. F2F). Additional aims were to investigate if student perceptions of learning epistemology and learning factors were related to course format. Students (n = 110)
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Over 3200 discrete soybean samples were obtained from production locations around the United States during the years 2012-2016. Ground samples were scanned on near infrared spectrometers (NIRS) and analyzed by HPLC for total isoflavone and total saponin composition, as well as total carbohydrate composition. Multiple Linear Regression (MLR) analysis of preprocessed spectral data was used to develop optimized models to predict isoflavone content
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To provide the basis for clinical diagnosis in an emergency case, a portable smartphone device-based multi-signal sensing system for on-site determination of alkaline phosphatase (ALP) is introduced. In this system, cobalt hydroxide (CoOOH) nanoflakes can oxidize O-phenylenediamine (OPD) to produce 2,3-diaminophenazine (OxOPD), resulting in a strong fluorescence at 565 nm and an absorbance at 420 nm, respectively. The
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34,95% CI 0.72 to 2.48, p <0.00001; RR=2.53,95% CI 1.62 to 3.93,p <0.0001;RR=29.5,95% CI 4.14 to 209.93, P=0.88).
The results of this meta-analysis indicate that vitamin D deficiency is associated with increased risk of liver cancer. The 25(OH)D3 levels are lower in HCC patients than those in health controls. Maintenance of sufficient serum vitamin D levels would be ben
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These characteristics of HUC-MSCs are discussed in the context of diabetes and its complications, liver disease, systemic lupus erythematosus, arthritis, brain injury and cerebrovascular diseases, heart diseases, spinal cord injury, respiratory diseases, viral infections, and other diseases. The second part emphasizes the need to establish an HUC-MSC cell bank, discusses tumorigenicity of HUC-MSCs and the characterist
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Double immunofluorescence assay indicated that the number of BM-EPC was significantly higher in TPO-treated group than in the control group. The TPO-treated BM-EPCs exhibited stronger tube-formation and migration abilities (
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Aromatase, a cytochrome P450 hemoprotein that is responsible for estrogen biosynthesis by conversion of androgens into estrogens, has been an attractive target in the treatment of hormone- dependent breast cancer. Design of new steroidal aromatase inhibitors becomes imperative.
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Clindamycin in low concentration (20 μg/mL) is safe for vitality and osteogenic potential of bone cells. The aim of this study was to evaluate the efficacy of local clindamycin (20 μg/mL) in two different exposure times, for microbial decontamination of particulate bone graft, collected during implant site preparation. This non-randomized parallel-group study was conducted on samples from 17 patients. The particulate
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A simple, efficient, environmentally friendly, and inexpensive synthesis route was developed to obtain a magnetic nano-hybrid (GH) based on graphene and cobalt ferrite. Water with a high content of natural organic matter (NOM) was used as solvent and a source of carbon. The presence of NOM in the composition of GH was confirmed by FTIR and Raman spectroscopy, which evidenced the format
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mNr and mTNrM staging systems can efficiently distinguish a survival difference in patients who undergo gastrectomy with ≤15 retrieved LNs, with
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Minocycline is a broad-spectrum antibiotic, effective as a chronic treatment for recurrent bacterial infections. Beyond its antibiotic action, minocycline also has important anti-inflammatory, antioxidant and antiapoptotic properties. Its efficacy has therefore been evaluated in many neurodegenerative and psychiatric diseases that have an inflammatory basis. Our aim was to review preclinical and clinical s
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Mutant KRAS promotes glutaminolysis, a process that uses steps from the tricarboxylic cycle to convert glutamine to α-ketoglutarate and other molecules, via glutaminase and solute carrier family 25 member 22 (SLC25A22). This results in inhibition of demethylases and epigenetic alterations in cells that increase proliferation and stem cell features. We investigated whether mutant KRAS-me
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These concepts support the RHH and PMH models and their further implementation as part of healthcare system transformation in Northern Ontario.
These concepts support the RHH and PMH models and their further implementation as part of healthcare system transformation in Northern Ontario.This is a report of a case of a 25-year-old woman, who presented with a rapidly progressi
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Further, the expression levels of filamin A (FLNA), integrin alpha-V (ITGAV), thymidine phosphorylase (TYMP), medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM), short-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADS), and acetyl-CoA acetyltransferase, mitochondrial (ACAT1) were examined through western blot and immunohistochemistry analysis, and the results confirmed the validity of the prot
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Already, the two-dimensional (2D) analysis of FISH and immunofluorescence data reveal the location of chromosomes as well as the different markings on the spermatic nucleus. In addition, a good 3D rendering after Imaris software processing was obtained when Z-stacks of images were acquired over a defined volume (10 μm × 13 μm × 15 μm) with a sequential scanning mode to minimize bleed-thro
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The model results demonstrate that modern lifestyle changes the chronotype distribution towards more eveningness and more extreme differences in eveningness. Such model-based predictions can be used to design guidelines for workplace lighting that help limiting circadian phase differences, and craft new lighting strategies that support human performance, health and wellbeing.During vocal communication, the spectro-tempora
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While use of augmentation of labor (AL) is appropriate for labor dystocia, it is frequently used inadequately and unnecessarily. The objective was to assess at a national level, the frequency and determinants of misuse of augmentation of labor (AL).
Women of the French perinatal survey of 2016 with a singleton cephalic fetus, delivering at term after a spontaneous labor were inc
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Diffuse intrinsic pontine glioma (DIPG) is an aggressive pediatric brainstem tumor. Most DIPGs harbor a histone H3 mutation, which alters histone post-translational modification (PTM) states and transcription. Here, we employed quantitative proteomic analysis to elucidate the impact of the H3.3K27M mutation, as well as radiation and bromodomain inhibition (BRDi) with JQ1, on
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RESULTS Compared with group B, the expression levels of HbA1c, 25(OH)D, PINP, FPG, FINS, HDL-C, and BSP mRNA were significantly increased while OPG and β-CTX were significantly decreased in group A. CONCLUSIONS The expression of BSP mRNA and the decrease of 25(OH)D and OPG in peripheral blood may participate in the development of diabetes and osteoporosis.Objectives The deleterious health effects of long working hours ha
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Research into carbon nanotubes (CNTs) has been a hot topic for almost 3 decades, and it is now that we are beginning to observe the impact of advanced applictions of this nanomaterial in areas such as electronics. Currently, in order to mass produce CNT devices, either large-scale synthesis, followed by numerous energy-intensive processing steps or photolithography processes, including
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They also bound to the three different human cancer cell lines, but not to the two cell lines as negative controls. They inhibited cell proliferation, migration and invasion and increased apoptosis of these three cancer cell lines. Two of them were tested for their anti-tumor effect in vivo and showed the anti-tumor activity in a mouse xenograft model for human lung cancer. Immunohistochemical staining of xenograft tumors a
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In summary, although hereditary and immunohistochemical scientific studies weren’t uniformly performed on all situations as a result of retrospective nature of this research, our data claim that discordant extramedullary plasmablastic transformation of numerous myeloma has an aggressive medical training course and it is described as regu
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Heterogeneous catalysts with atomically precise metal sites have enabled unique insight into structure-property relationships in materials science. Herein, we report the construction and selective hydrogenation performance of a single-atom palladium catalyst by confining the palladium atoms into the six-fold N-coordinating cavities of graphitic carbon nitride (g-C3N4) through a facile spatial confinement-reduction appr
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Parkinson’s disease (PD) is a common neurodegenerative disorder, characterised by the presence of motor disturbances. Therefore, it can be related to musculoskeletal and orthopaedic problems, particularly in the foot status, that are linked to a negative effect on overall health, mobility and social function.
The aim was to analyse the impact of foot health and qualit
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Furthermore, the morphology and particle size distribution of the polymersomes were also investigated by using transition electron microscopy, dynamic light scattering, and field emission scanning electron microscopy.Time-varying neurophysiological activity has been classically explored using correlation based sliding window analysis. However, this method employs only lower order statistics to track dynamic functional con
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On average, 37% of debriefing questions were analyzed (range, 0% to 69%), and the results were used less then 50% of the time, usually to exclude respondents or interpret overall results. Researcher experience or confidence with DCEs did not affect their use of debriefing questions. CONCLUSIONS These results suggest that although half of researchers conducting health DCEs use debriefing questions, many do not analyze, use
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Background Having a penicillin allergy label associates with higher risk for antibiotic resistance and increased healthcare use. Objective To assess the accuracy of skin tests and specific IgE quantification in the diagnostic evaluation of patients reporting a penicillin/β-lactam allergy. Methods We performed a systematic review and diagnostic accuracy meta-analysis, searching on MEDLINE, Scopus and Web of Science. We incl
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To evaluate changes in self-reported depression after treatment of fecal incontinence (FI) with sacral neuromodulation.
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MacroD2 is one of the three human macrodomain proteins characterized by their protein-linked mono-ADP-ribosyl-hydrolyzing activity. MacroD2 is a single-domain protein that contains a deep ADP-ribose-binding groove. In this study, new crystallization conditions for MacroD2 were found and three crystal structures of human MacroD2 in the apo state were solved in space groups P41212, P43212 and P43, and refined at 1.75, 1.90 and 1
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Each of the COMI domains and the COMI summary score correlated to the hypothesized extent with the scores of the reference questionnaires (ρ = 0.40-0.79). According to the ROC curve with satisfaction (including “very satisfied” and “satisfied”), the area under the curve and MCID of the COMI summary score were 0.78 and 2.1. The intraclass correlation coefficient and the minimum detectable change (MDC 95%) of the
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The art of diagnosis is of great importance in the management of any disease. This includes preventive and therapeutic strategies. To make an accurate and effective diagnosis, knowledge about the health-disease process is fundamental. This paper reviews the important aspects for periodontal diagnosis in a contemporary approach, and endeavors to establish challenges for improving periodontal diagnosis, especially
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The median prednisolone dose was reduced from 30 mg (range 7.5-60 mg) to 5 mg (range 0-10 mg) after biological therapy (P = 0.002). Significant visual improvement was observed post biologic therapy (mean log mar VA 0.41 ± 0.62 improved to 0.23 ± 0.48 at the final visit, P = 0.008). Maximum number of patients (16 patients, 89%) responded well with biological therapy. Three patients developed recurrence and systemic com
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