Burnie Burns, born as Michael Justin Burns, is the CEO of RoosterTeeth and the creator of Red v. Blue and Lazer Team, along with other projects created under RoosterTeeth. Burnie was born in New York, but has lived most of his life in Austin, Texas, where RoosterTeeth is currently located.
In his early life, he went to Alief Elsik High School, where he got the nickname “Burnie.” It was given to him by a classmate who wanted to differentiate him between the other Michael’s in his class. He then went on to go to The University of Texas at Austin. Here, he started working on the campus TV station. While he was there, he started a new TV program Sneak Peak, which is the longest running student television show at The University of Texas at Austin.
While attending school, he was working at a tech company where he met future co-founders of RoosterTeeth, Geoff Ramsey and Gus Sorola. As they started working together, they started to develop a new, game changing video-game based videos. The videos were called Red v. Blue. They used a technique called machinima, which means to take pre-recorded game play from a video game and dub audio over top to make create a story. When they first used this technique, it was widely disregarded, and nobody really paid any attention to the series. After they got recognition from Computer Gaming World, the series became so popular, that they had to revise their original thought of only making these short, comedic videos to a full season length, consisting of 20 episodes or so per season.
Because of the popularity they were getting, the decided to make their own website, properly named redvblue.com. Their domain name has since changed to RoosterTeeth.com, because after Red v. Blue, their company grew beyond their imaginations. Over the course of the next couple of years, they went on to make more machinima content, like The Strangerhood and PANICS. These shows made their popularity grow even more, so Burnie had to grow his company.
Presently, they have made a lot of great content. To name some, Immersion, where they take video game situations and try to replicate them in real life, RWBY, being a very popular anime show, and The RoosterTeeth Podcast, where his co-founder, Gus Sorola, hosts a podcast every week and has guests through out the company talk about recent events and popular topics.
Because of them, they have inspired me to pursue the Communication Media field so i can one day hopefully work for them. To hear their story, to have them come up from nothing and create such a successful company, who has produced a Blockbuster movie called Lazer Team, it has motivated me to learn all i can about production and editing.
Have you ever heard of these guys? Do you love them as much as i do? Let me know in the comments below about what you think!
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It has been computationally proposed that there are more than 200 possible isomeric structures for the C6H6 molecule, among which benzene (CH)6 represents the most thermodynamically stable molecule and its chemistry has been extensively developed. Three benzene valence isomers (CR)6, namely, prismane, Dewar benzene, and benzvalene, have also been synthesized to date. Incorporation of heteroatoms in the skeletal framewor
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1 mg/mL and 0.5 mg/mL), taking advantage of high-content analysis tools. The proposed HT-loaded nanoscaffolds are non-toxic to cells, and their administration showed a significant decrease in the intracellular triglyceride levels, restoring cell viability and outperforming the results achievable with HT in its non-encapsulated form. Moreover, nanogels do not induce oxidative stress, thus demonstrating their biosafety. Overall, th
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Ring sideroblasts show abnormal mitochondrial iron accumulation, and their emergence in the bone marrow is a characteristic of sideroblastic anemias (SAs). SAs are a group of heterogeneous congenital and acquired disorders. Congenital SA is a rare disease caused by gene mutations involved in heme biosynthesis, iron-sulfur cluster biosynthesis, and mitochondrial protein synthesis. SAs can also occur after exposure to certain drugs o
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Mankind has long utilized Cannabis for diverse purposes. However, it has only been since the late 19th century that its individual cannabinoids began to be isolated, analyzed, and synthesized. By the mid-20th century it was discovered that many cannabinoids were asymmetric, with chirality often controlling their pharmacology. Increasingly accurate measurement and understanding of cannabinoid chirality
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To characterize monocyte subsets and activation in persons living with HIV (PLWH) with tuberculosis coinfection.
Cross-sectional study within a cohort of PLWH and HIV-uninfected participants at the Joint Clinical Research Centre in Kampala, Uganda.
Participants were at least 45 years old with at least one car
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Purpose MicroRNA-769-5p (miR-769) is aberrantly expressed and plays crucial roles in non-small cell lung cancer and melanoma. However, the expression pattern, biological role, and mechanisms of action of miR-769 in pancreatic ductal adenocarcinoma (PDAC) are yet to be fully elucidated. Therefore, we attempted to determine the potential regulatory function of miR-769 in PDAC progression and to explore the underlying
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42; 95% confidence interval [95% CI] 0.67-4.17;
= 0.008) and risperidone group (3.40; 95% CI 0.54-6.25;
= 0.021). Urinary melatonin was significantly decreased in both haloperidol (
= 0.005) and risperidone group (
= 0.014). PSQI score was significantly increased in both haloperidol (
= 0.001) and risperidone group (
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Our findings suggest that TRF regimen might be a potential novel nonpharmacological strategy against obesity/diabetes-induced hyperglycemia and insulin resistance.Resilience means “the ability to withstand or recover quickly in the face of adversity”. Elucidating the neural and molecular mechanisms underlying stress resilience will facilitate the development of more effective treatments for stress-induced psyc
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and have high mortality. Modifiable hospital practices around the escalation of care for these high-risk patients may contribute to poor outcomes. Earlier recognition of critical illness and timely ICU transfer may improve survival in hospitalized children with cancer.
To analyze the predictive factors for non-sentinel lymph node (non-SLN) metasta
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l interventions should be considered for improving antenatal care utilization and better health outcomes. The government should give special attention to the regions like Afar, Amhara, Oromia, Benishangul, SNNP, and Somalia which had low optimal ANC visits.BACKGROUND Gestational diabetes mellitus is associated with increased incidence of adverse perinatal outcomes including newborns large for gestational age, macros
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Our study revealled the graft MaS affected the post-transplant outcomes in lower risk cutoff in Chinese patients. Further study is worthy to validate these results and investigate inner mechanism under the phenomenon.
Our study revealled the graft MaS affected the post-transplant outcomes in lower risk cutoff in Chinese patients. Further study is worthy to validate these results and investiga
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Our result showed that a titer of 2.02 ± 0.40 mg/L (plasmid) and 0.41 ± 0.06 mg/L (integrated) can be achieved using these strategies. This platform strain can be used to readily test the gene candidates for microbial paclitaxel biosynthesis in the future.Direct-to-consumer genetic tests (DTC-GT) have become a bridge between marketing and traditional healthcare services. After e
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Traditional rehabilitation services, whether they are cardiac, pulmonary, or vascular, consist of 6-36 center-based, supervised sessions; however, due to COVID-19, in-person visits were suspended. This study sought to implement a transitional home-based treatment plan (HBTP) to patients.
Patients enrolled in a rehabilitation service at the Miriam Hospital during the time of temporar
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KEGG Enrichment analysis reveals that the significant enrichment pathways had 6 pathways, including secondary metabolite biosynthesis, phenylpropanoid biosynthesis, indole alkaloid biosynthesis, photosynthesis, plant hormone signaling, and plants-pathogen interactions, and 24 related DEGs were detected by RT-qPCR, the result of which was significantly correlated with the transcriptome data.
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Epithelial-mesenchymal transition (EMT), which is involved in metastasis formation, requires reprogramming of gene expression mediated by key EMT transcription factors. However, signals from the cellular microenvironment, including hypoxia, can also modulate the process of EMT. Hypoxia is often associated with a reduction in the extracellular pH of the tumor microenvironment (acidosis). Whether acidosis alone h
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Pollarding of oak trees for livestock and animal feeding is a traditional application, and it has been used for centuries from generation to generation in southern and southeastern Turkey. Estimation of the fresh sprout biomass (FSB) potential of pollarded oak forests in high accuracy is important for sustainable forest management. In the present study, 40 trees were sampled from Turkey oak (Quercus cerris L.) stands
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The autoaggregation of Ethanoligenen facilitated its granulation with acetate-oxidizing bacteria in co-culture systems and mitigated a fast pH drop, providing a new approach for solving a pH imbalance and improving hydrogen production. In-depth studies of the regulatory mechanism underlying ethanol-H2 co-production metabolism and the syntrophic interactions of ethanol-H2 co-producing Ethanoligenens with other microorga
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Mass transfer of guest molecules has a significant impact on the applications of nanoporous crystalline materials and particularly shape-selective catalysis over zeolites. Control of mass transfer to alter reaction over zeolites, however, remains an open challenge. Recent studies show that, in addition to intracrystalline diffusion, surface barriers represent another transport mechanism that may dominate the overall ma
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In our ever-shifting world, understanding the central concepts that shape various industries is more essential than ever. Today, we delve into the meaning and significance of this term and explore how it shapes various disciplines. Whether you’re someone seeking knowledge, knowing the ins and outs of this concept</stro
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Because of endoscopist fatigue, the time of colonoscopy have been shown to influence adenoma detection rate (ADR). Computer-aided detection (CADe) provides simultaneous visual alerts on polyps during colonoscopy and thus to increase adenoma detection rate. This is attributable to the strengthening of endoscopists diagnostic level and alleviation of fatigue. The aim of the study was to investigate wheth
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Two-dimensional electrons confined to GaAs quantum wells are hallmark platforms for probing electron-electron interactions. Many key observations have been made in these systems as sample quality has improved over the years. Here, we present a breakthrough in sample quality via source-material purification and innovation in GaAs molecular beam epitaxy vacuum chamber design. Our samples display an ultra-high mobility of
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in is not considered a K. pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) or a carbapenem-resistant K. pneumoniae (CRKP) as it is usually. Further follow-up and research are required to investigate this strain.
Hepatitis E virus (HEV) is an emerging infectious agent that causes acute hepatitis in developing and developed countries. Diagnosis of HEV infection has not been routinely done in Egyptian hos
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Spinal cord injury (SCI) can cause chronic paralysis and incontinence and remains a major worldwide healthcare burden, with no regenerative treatment clinically available. Intraspinal transplantation of olfactory ensheathing cells (OECs) and injection of chondroitinase ABC (chABC) are both promising therapies but limited and unpredictable responses are seen, particularly in canine clinical trials. Sustained
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In today’s fast-changing world, the concept of biological diversity has taken center stage in discussions about environmental conservation and sustainability. Understanding this crucial element in our natural world is essential for ensuring the longevity of our planet. This article aims to examine why biodiversity is vital and how it impacts various facets
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7 nm) line intensity (2.3), followed by zeolite-modified COPUF (Z/COPUF) (1.9), and activated carbon-modified COPUF (AC/COPUF) (0.2), which indicates the adsorption performance of Pb2+ on the respective materials. The heavy metal ions’ adsorption on the B/COPUF dominantly resulted from the electrostatic attraction. This study demonstrated the potential use of B/COPUF in adsorption and LIBS quantitative analysis
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However, the production of the heterologous xylanase and the secretion of total proteins were not altered by deleting the same genes. Considering the results, this approach demonstrated the possibility of rationally increase the production of a homologous enzyme, indicating that trxA, cypA, ydjA and pbnA are involved in protein production by A. nidulans. © 2020 The Authors. Microbial Biotechnology published by Joh
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Rapid yet accurate detection of disease-related biomarkers is key for point of care testing, where there is an increasing demand for multi-index analysis. Here, we present a versatile device for multianalyte quantification based on the microfluidic technique and electrochemical sensor array. The analytes were shunted through inner-built channels to screen-printed electrodes installed at different positions o
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Furthermore, these results open new perspectives for knowledge of the mechanisms that underlie the higher percentage of Treg cells found in peripheral blood of PCM patients.Traditional statistical analyses of randomized clinical trials typically employ p-values within a null hypothesis significance testing paradigm. Clinical adoption of randomized trials results, by both guideline writers and individu
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Recent data indicate that acute kidney damage leads to inflammation in the brain and other distant organs. The purpose of this study was to investigate the effect of acute kidney injury (AKI) according to the Kidney Disease Improving Global Outcome (KDIGO) criteria on the occurrence of postoperative delirium in patients undergoing coronary artery bypass grafting (CABG). We performed a retrospective cohort a
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The study was designed to quantify value and the spatial distribution of key ecosystem services such as wood production, habitat for biodiversity, carbon sequestration and air quality regulation in two areas Ereğli and Yeşilkuşak of Turkey. Wood production was quantified using forest inventory data and yield tables. Carbon storage was estimated based on the above – and below – ground biomass, deadwood and litter a
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A method of predicting cellular drug inhibition due to heat stress is presented. Black phosphorus nanosheets are used as photothermal agents to induce stress granule formation in tumor cells. The addition of different drugs induces different thermal stress responses. The features of single-photon images are automatically extracted and analyzed by a convolutional neural network algorithm for classification and recogniti
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Several existing models explaining the origin of multicellular animals have been put forward, but these data are interestingly consistent with one, the “synzoospore hypothesis.” CONCLUSIONS The feeding modes of the ancestral metazoan may have been more complex than previously thought, including not only bacterial prey, but also larger eukaryotic cells and organic structures. The ability to feed on large e
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Other changes were statistically nonsignificant.
In Japanese medical schools, the number of class meetings teaching Kampo medicine has increased; however, this number is not statistically significant. Persistent problems in Kampo education, including curriculum standardisation, need to be addressed.
In Japanese medical schools, the nu
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Theabrownin (TB), a natural compound present in the fresh leaves of green tea, is a potential antitumor agent. However, so far whether and how TB affects glioma is unclear. In this study, we investigated the effect of TB on astroglioma and oligodendroglioma cells. Surprisingly, TB significantly reduced the viabilities of HOG and U251 cells in a dose-dependent manner, which was accompanied by the upreg
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Finally, post-infection viral kinetics were similar between all groups. Thus, although probiotics were well-tolerated when administered with SIV/HIV vaccination, vaccine-specific responses were not significantly enhanced. Additional work will be necessary to develop more effective strategies of microbiome modulation in order to enhance mucosal vaccine immunogenicity and improve protective immune responses.AP
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Mammalian STE20-like protein kinases (MST), including MST1, MST2, MST3, and MST4, belong to the germinal center kinase (GCK) family. Kinase MST1/2 is an important component of the Hippo pathway in regulating cell proliferation, tissue homeostasis, and organ development. Recent studies have shown that Hippo kinase MST1/2 plays a crucial role in immune-associated diseases, which has attracted extensive attention
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Somapacitan is a long-acting, once-weekly, albumin-binding growth hormone (GH) derivative. The reversible albumin-binding properties leads to prolonged circulation half-life. Here, we investigated and compared somapacitan with human GH on downstream receptor signaling in primary hepatocytes and hepatocellular models and using isothermal titration calorimetry to characterize receptor binding of somapacitan in t
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Ovarian cancer is the most lethal gynecologic malignancy. Poly (ADP-ribose) polymerase inhibitors (PARPi) are effective in treating ovarian cancer. However, cancer cell insensitivity and resistance remain challenges. Determination of the exact chemoresistance mechanisms and potential targeted therapies is urgent. CDCA8 (cell division cycle associated 8) participates in the tumorigenesis of various cancers; h
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Conclusion Our results yield further support the for the view that TNF-α inhibitors increase body weight and BMI as a potential side effect. Modulating cytokine signaling could be a future therapeutic mechanism to treat disorders associated with weight changes such as anorexia nervosa. Copyright © 2020 Patsalos, Dalton, Leppanen, Ibrahim and Himmerich.Mitophagy is a crucial process in controlling mitochondria
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Melanoma is a fast-growing tumour in dogs and represents 7% of the total malignant neoplasms from the skin and is the most common tumour found in the oral cavity. In these tumours, high expression of cyclooxygenase-2 (COX-2) is associated with a poor prognosis. The aim of this study was to verify if the overexpression of COX-2 is related to the modulation of lymphocytes and if it i
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