Burnie Burns, born as Michael Justin Burns, is the CEO of RoosterTeeth and the creator of Red v. Blue and Lazer Team, along with other projects created under RoosterTeeth. Burnie was born in New York, but has lived most of his life in Austin, Texas, where RoosterTeeth is currently located.
In his early life, he went to Alief Elsik High School, where he got the nickname “Burnie.” It was given to him by a classmate who wanted to differentiate him between the other Michael’s in his class. He then went on to go to The University of Texas at Austin. Here, he started working on the campus TV station. While he was there, he started a new TV program Sneak Peak, which is the longest running student television show at The University of Texas at Austin.
While attending school, he was working at a tech company where he met future co-founders of RoosterTeeth, Geoff Ramsey and Gus Sorola. As they started working together, they started to develop a new, game changing video-game based videos. The videos were called Red v. Blue. They used a technique called machinima, which means to take pre-recorded game play from a video game and dub audio over top to make create a story. When they first used this technique, it was widely disregarded, and nobody really paid any attention to the series. After they got recognition from Computer Gaming World, the series became so popular, that they had to revise their original thought of only making these short, comedic videos to a full season length, consisting of 20 episodes or so per season.
Because of the popularity they were getting, the decided to make their own website, properly named redvblue.com. Their domain name has since changed to RoosterTeeth.com, because after Red v. Blue, their company grew beyond their imaginations. Over the course of the next couple of years, they went on to make more machinima content, like The Strangerhood and PANICS. These shows made their popularity grow even more, so Burnie had to grow his company.
Presently, they have made a lot of great content. To name some, Immersion, where they take video game situations and try to replicate them in real life, RWBY, being a very popular anime show, and The RoosterTeeth Podcast, where his co-founder, Gus Sorola, hosts a podcast every week and has guests through out the company talk about recent events and popular topics.
Because of them, they have inspired me to pursue the Communication Media field so i can one day hopefully work for them. To hear their story, to have them come up from nothing and create such a successful company, who has produced a Blockbuster movie called Lazer Team, it has motivated me to learn all i can about production and editing.
Have you ever heard of these guys? Do you love them as much as i do? Let me know in the comments below about what you think!
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Background The orbit is an anatomically complex structure comprising the globe, extraocular muscles, fat, vascular, nervous, glandular, and connective tissues. A wide variety of neoplasms can arise from different orbital structures, which can create a diagnostic challenge to the pathologists. No formal study has been conducted in this regard in North East India. Aim and Objectives This article aims to document the pattern a
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Baseline characteristics were similar between groups. The proportion of patients receiving timely guideline-based therapy was significantly higher in the post-intervention cohort compared to the pre-intervention cohort (76.5% vs 34.4%, p less then 0.001), primarily driven by increased ordering of vitamin K 10 mg IV in conjunction with PCC in the post-intervention cohort. Our results indicate tha
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This review introduces the mechanism of hypothermia and its application in the eye banks, eye diseases (allergic conjunctivitis, retinal ischemia, and hypoxia), and eye surgeries (corneal transplant surgery, corneal refractive surgery, and vitrectomy).Heat shock factor 1 (HSF1) is a transcription factor involved in the heat shock response and other biological processes. We have unveiled here an important role of HSF1
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The present work exploits the tumor microenvironment which differs significantly from normal cellular environment in terms of both, having lower extracellular pH and increased angiogenesis capacity. To reduce systemic toxicity of docetaxel (DTX) and increase its therapeutic potential, VEGF antibody functionalized PEGylated pH sensitive liposomes (VEGF-PEG-pH-Lipo-DTX) were developed. The
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เลือกเกมคาสิโนไลฟ์สด ด้วยความนิยมชมชอบที่มากขึ้นของคาสิโนออนไลน์ ทำให้มีเว็บที่ให้บริการกลุ่มนี้ มากขึ้นอย่างเร็ว แต่ คาสิโนออนไลน์ทั้งสิ้นมิได้ถูกผลิตขึ้น มาเสมอภาค มีคาสิโนออนไลน์ชั้นหนึ่งบางที่ที่เด่นกว่าที่เหลือ โดยเสนอตัวเลือกเกมรวมทั้งรางวัลรายวันมากไม่น้อยเลยทีเดียวให้กับผู้เล่น คาสิโนที่ได้รับการจัดชั้นสูงสุดพวกนี้ คาสิโนครบถ้วนบริบูรณ์เรื่องพนัน มักร่วมมือกับผู้ให้บริการโปรแกรมคอมพิวเตอร์ที่มีชื่อ ยกตัวอย่างเช่น Microgaming, NetEnt และก็ Playtech ฯลฯ เพื่อมั่นใจว่าผู้เล่นสามารถ
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There was significant increase in LAA PW Doppler velocities (LAAEDE, LAALDE and LAAF velocity) immediately Post PTMC which got further improved significantly at 6 months of follow up. There was significant increase in LAA DTI velocities (E
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A woman in her 40s visited our hospital for further examination and treatment of a left renal tumor. Imaging studies showed that the patient had a large left renal tumor, 10.5 cm in diameter, which contained foci of necrosis. Open left radical nephrectomy was performed. In pathological examination, hematoxylin-eosin staining showed uniform small round cells with alveolar growth. Immunohistochemistry findings showed
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We further reconstructed the transcriptional regulating network governing human and RO retinogenesis in vivo. Particularly, NFIB and THRA were identified as regulators in individual retinal development. The chromatin adjustments between developing individual and mouse retina were additionally cross-analyzed. Notably, we unveiled an enriched bivalent modification of H3K4me3 an
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n the cecal digesta was positively correlated with the concentration of B. subtilis-fermented products under LPS challenge. These results demonstrate that B. subtilis-fermented products can improve the growth performance and modulate the gut microflora composition of broilers under immune stress.The effect of docosahexaenoic acid (DHA, 226 n-3)-rich microalgae and methionine (Met) supplementation on productio
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r at least one previous antidepressant treatment, had a significantly lower post-treatment depression severity with CBASP compared to SP (all p less then 0.05). Conclusions and relevance A complex multifactorial interaction between severe symptoms of depression, suicidality, and traumatic childhood experiences characterized by abuse, social inhibition, and anxiety may repre
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Objective Brain mapping with direct electrical stimulation is considered the gold standard for maximum, safe resection of tumors affecting eloquent regions. However, no consensus exists in selection and interpretation of intraoperative testing for language and other cognitive domains. Our aim was to capture and statistically analyze variability in current practices in intraoperative languag
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This analysis attempts to determine the diagnostic and prognostic value of bone marrow (BM) evaluation by multiparameter flow cytometry in patients with myelodysplastic syndrome (MDS).
The study group consisted of patients who underwent diagnostic process in the years 2008-2017 due to cytopenia and finally were diagnosed with MDS (n=71). The comparative group included pat
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Antigen transfer from pDCs to cDCs was mediated by previously unreported pDC-derived exosomes (pDCexos), that were also produced by pDCs under various conditions. Importantly, all these pDCexos primed naive antigen-specific CD8 T cells only in the presence of bystander cDCs, similarly to cross-presenting pDCs, thus identifying pDCexo-mediated antigen transfer to cDCs as a mechanism for pDCs to achieve cross-priming. In
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Persistent antigen exposure leads to the accumulation of lymphocytes and subsequent tertiary lymphoid structures (TLS). We investigated the relationship of tumor microenvironment (TME) with respect to programmed death ligand 1 (PD-L1), its receptor programmed death 1 (PD-1), and TLS in upper tract urothelial carcinoma (UTUC) cases and compared them with UTUC associated with
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High-risk human papillomavirus (HR-HPV) is an important risk factor for esophageal cancer. Macrophages constitute a crucial immune medium for regulating HPV-related tumors; however, the specific regulatory mechanisms remain unknown. Therefore, the purpose of our current study was to investigate the mechanism by which HPV16E6 regulates macrophages to promote the invasion and metastasis of esophageal cancer
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IMPLICATIONS FOR NURSING MANAGEMENT To highlight nursing priorities, we suggest that the fundamental need for nursing care and what this implies for patient care in different organizational settings be clarified and that policymakers explicitly include this information in national policy documents. This article is protected by copyright. All rights reserved.”Chemistry is fun because it is strongly unpredic
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Corneal endothelial (CE) dysfunction is the main indication for corneal transplantation, an invasive procedure with several limitations. Developing novel strategies to re-activate CE regenerative capacity is, therefore, of fundamental importance. This goal has proved to be challenging as corneal endothelial cells (CEnC) are blocked in the G0/G1 phase of the cell cycle in vivo and, albeit retaining proliferativ
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Drought is a major factor limiting crop productivity and quality. Sucrose non-fermenting-1 (SNF1)-related protein kinase 2s (SnRK2s) play critical roles in plant abiotic stress responses, especially in drought stress. However, knowledge regarding the functional roles of SnRK2s in drought stress and their underlying mechanisms is relatively limited in tea plant. In this study, CsSnRK2.5, a PEG
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Using survival analysis and Cox regression model, we identified a set of seven lncRNAs (LINC00941, FAM83A-AS1, AC026355.1, AC068338.3, AC010980.2, AL365181.2, and AC079949.2) demonstrating an ability to stratify patients into high and low risk groups with significantly different survival outcomes. Moreover, the signature was identified as an independent prognostic factor and significantly associated with t
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Hence understating the impact of dietary phytochemicals on human health and their molecular mechanism will thrive a new horizon in cancer therapeutics. Hence, this review has emphasized the role of apoptotic/autophagy modulating dietary phytochemicals in cancer therapy, their preclinical and clinical applications and the future direction of enhanced nano-formulation for better clinical efficacy.We describe an elderly mal
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To evaluate the outcomes of Ilizarov external fixator (IEF) and minimal invasive surgery (MIS) in correction of neglected club foot (NCF).
Thirty-seven feet in 24 child, between five and 15years old were diagnosed as NCF. All were treated with Achilles tendon lengthening (ATL) and IEF for gradual correction. After IEF removal, cast was applied for six weeks to maintain co
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Stair climbing is an intense physical activity and requires large range of motion at the joints, adequate muscle strength, and balance control. A powered stairmill, integrated with a gait rehabilitation device, can potentially be used for training those who have difficulty climbing stairs. In order to assess the effectiveness of such an approach, it is necessary to understand the similarities and differences in walking on r
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Participants tested 72 hours after training demonstrated improved performance in a test that directly recapitulated training (Wilcoxon matched-pairs signed-rank test; two-tailed p all ≤ .001). There were no significant differences between EAT and EMT in this test (Mann-Whitney U test and Welch’s t-test; two-tailed p ≥ .26) or in short- and long-term adaptive transfer tests (p ≥ .22). Survey data indicate that parti
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Perfluorinated compounds like perfluorooctanesulfonic acid (PFOS) are synthetic water pollutants and have accumulated in environments for decades, causing a serious global health issue. Conventional assays rely on liquid chromatography and mass spectroscopy that are very expensive and complicated and thus limit the large-scale monitoring of PFOS in wastewater. To achieve low-cost and accurate detection of PFOS, we designed
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Results demonstrate that allocation to competition gives males greater fitness than offspring care for a range of circumstances that are dependent on life-history parameters and, for the large-game hunting application, frequency dependent. The greater the collective benefit, the more individuals can be selected to supply it.
This survey conducted by the International Society of Radiology an
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e pain and pelvic cavity pain, but only the association with pelvic cavity pain stayed significant after adjustment for depression. CONCLUSION This study showed that sleep complaints in early pregnancy are common, and sleep complaints showed association with physical as well as mental symptoms. It may be important for pregnant patients that clinicians address depression, and mood in relation to sleep problems dur
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Baseline characteristics were similar between groups. The proportion of patients receiving timely guideline-based therapy was significantly higher in the post-intervention cohort compared to the pre-intervention cohort (76.5% vs 34.4%, p less then 0.001), primarily driven by increased ordering of vitamin K 10 mg IV in conjunction with PCC in the post-intervention cohort. Our results indicate that implementati
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Chopped pepper is one of the traditional fermented pepper products in China. At present, the industrial production method is mainly to preserve the peppers with high salt about 1 year, and then make the product after desalination and seasoning when it is processed. However, the composition and succession of the bacterial community involved in the long-term preservation of salted pepper was complex. In this study,
เลือกเกมคาสิโนไลฟ์สด ด้วยความชื่นชอบที่มากขึ้นของคาสิโนออนไลน์ ทำให้มีเว็บที่ให้บริการพวกนี้ มากขึ้นอย่างเร็ว อย่างไรก็แล้วแต่ คาสิโนออนไลน์ทั้งหมดทั้งปวงมิได้ถูกผลิตขึ้น มาเสมอภาค มีคาสิโนออนไลน์ชั้นหนึ่งบางพื้นที่ที่เด่นกว่าที่เหลือ โดยเสนอตัวเลือกเกมรวมทั้งรางวัลรายวันเยอะมากให้กับผู้เล่น คาสิโนที่ได้รับการจัดชั้นสูงสุดพวกนี้ คาสิโนครบถ้วนบริบูรณ์เรื่องพนัน มักร่วมมือกับผู้ให้บริการโปรแกรมคอมพิวเตอร์ที่มีชื่อ อย่างเช่น Microgaming, NetEnt และก็ Playtech ฯลฯ เพื่อมั่นใจว่าผู้เล่นสามาร
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Understanding of the factors governing immune responses in cancer remains incomplete, limiting patient benefit. In this study, we used mass cytometry to define the systemic immune landscape in response to tumor development across five tissues in eight mouse tumor models. Systemic immunity was dramatically altered across models and time, with consistent findings in the peripheral blood of patients with breast cance
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Aim We retrospectively evaluated the role of neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-monocyte ratio (LMR) as prognostic factors in metastatic non-small-cell lung cancer patients treated with nivolumab. Materials & methods Medical records of 65 patients were reviewed. NLR and LMR were calculated at baseline (t0) and at first radiological tumor assessment (t1). Results At univariate analysis, low NLR
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Yet, GFP-tagged Drp1 retains the capacity to mediate membrane constriction in vitro and mitochondrial division in vivo. These findings suggest that instead of robust assembly-disassembly dynamics, persistent Drp1 higher-order oligomerization over membranes is sufficient for mitochondrial fission.Halide vacancy defect is one of the major origins of non-radiative recombination in the lead halide perovskite light
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The expression of Ki67 gene indicated an increase in ovarian cell proliferation in the three experimental groups compared to the control group, however this increment was only significant for the bFGF + KL group. It can be concluded that KL and bFGF factors individually have no beneficial effects on in-situ follicular growth, but their combination positively influences steroidogenesis of granulosa cells without signifi
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Clinical implications and future research directions are discussed.Overall, the retention of people with serious mental illness (SMI) in supportive housing is high. However, some supportive housing settings report average stays of only 15 months, and others report declines in housing retention over time. Many studies report variables associated with supportive housing stability and tenure, but there are few exte
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In this review, we will discuss the immunological basis and the latest advances of the use of checkpoint inhibitors to treat HIV infection.Background The tumor microenvironment (TME) consists of heterogeneous cell populations, including malignant cells and nonmalignant cells that support tumor proliferation, invasion, and metastasis through extensive cross talk. The intra-tumor imm
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Here, (MTS)(SA) and (MTS)(W) were more and minimum steady cluster, respectively. MD simulations were used for time and spatial evaluation associated with the role of this MTS-SA system. The results indicated that MTS can self-aggregate or absorb SA particles into groups, larger than how big is the crucial group (approximately 1 nm), suggesting that MTS can initiate NPF on it’s own or togeth
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