Burnie Burns, born as Michael Justin Burns, is the CEO of RoosterTeeth and the creator of Red v. Blue and Lazer Team, along with other projects created under RoosterTeeth. Burnie was born in New York, but has lived most of his life in Austin, Texas, where RoosterTeeth is currently located.
In his early life, he went to Alief Elsik High School, where he got the nickname “Burnie.” It was given to him by a classmate who wanted to differentiate him between the other Michael’s in his class. He then went on to go to The University of Texas at Austin. Here, he started working on the campus TV station. While he was there, he started a new TV program Sneak Peak, which is the longest running student television show at The University of Texas at Austin.
While attending school, he was working at a tech company where he met future co-founders of RoosterTeeth, Geoff Ramsey and Gus Sorola. As they started working together, they started to develop a new, game changing video-game based videos. The videos were called Red v. Blue. They used a technique called machinima, which means to take pre-recorded game play from a video game and dub audio over top to make create a story. When they first used this technique, it was widely disregarded, and nobody really paid any attention to the series. After they got recognition from Computer Gaming World, the series became so popular, that they had to revise their original thought of only making these short, comedic videos to a full season length, consisting of 20 episodes or so per season.
Because of the popularity they were getting, the decided to make their own website, properly named redvblue.com. Their domain name has since changed to RoosterTeeth.com, because after Red v. Blue, their company grew beyond their imaginations. Over the course of the next couple of years, they went on to make more machinima content, like The Strangerhood and PANICS. These shows made their popularity grow even more, so Burnie had to grow his company.
Presently, they have made a lot of great content. To name some, Immersion, where they take video game situations and try to replicate them in real life, RWBY, being a very popular anime show, and The RoosterTeeth Podcast, where his co-founder, Gus Sorola, hosts a podcast every week and has guests through out the company talk about recent events and popular topics.
Because of them, they have inspired me to pursue the Communication Media field so i can one day hopefully work for them. To hear their story, to have them come up from nothing and create such a successful company, who has produced a Blockbuster movie called Lazer Team, it has motivated me to learn all i can about production and editing.
Have you ever heard of these guys? Do you love them as much as i do? Let me know in the comments below about what you think!
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To develop an information model to support secondary use of data using electronic health records.
Retrospective observational data-driven study with secondary use of data. The sample was composed of structured data from all adults admitted to clinical and surgical inpatient units of a public university hospital. Data between June 2014 and July 2019 were included, tota
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Nebulized budesonide has been long used in chronic obstructive pulmonary disease (COPD) exacerbation. This study aimed to compare the effectiveness of nebulized budesonide (NB) versus oral prednisolone (OP) in increasing peak expiratory flow rate (PEFR) of COPD patients in emergency department (ED).
Patients with COPD exacerbation, referring to ED w
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No technical difficulty was encountered regarding the use of endoscopic technique. “Helpful” fluorescence staining was observed in 16 patients and fluorescent tissue was completely removed. Postoperative MRI confirmed gross total resection (88.9%). In 2 patients, FS enhancement was not helpful enough for tumor demarcation and postoperative MRI revealed near total resection (11.1%). No complication, adverse events, or si
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01, hazard ratio 7.05 [1.45-34.20]). Hematoma volume or extramuscular retroperitoneal hematoma had no significant influence on short-term mortality.
Only active bleeding but not hematoma volume or extra-muscular bleeding is an independent risk factor for short-term mortality in patients with SIPH.
Only active bleeding but not hematoma volume or
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012 and 0.014 µmol/L, and the limits of quantification (LOQ) were 0.039 and 0.045 µmol/L, respectively. Satisfactory results were observed for linearity (R2 > 0.999), intra-day precision (RSD% less then 7.7% in FaSSIF-V2 and less then 6.6% in HBSS), inter-day precision (RSD% less then 5.9% in FaSSIF-V2 and less then 5.6% in HBSS), accuracy (% error within ± 10%), and sample stability (RSD% less then 7.7% and % error
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Many adults suffering from ADHD also suffer from comorbid conditions like major depressive disorder (Kessler and colleagues 2006). Many people who suffer from depression do not respond well to medications and may be able to benefit from therapy.
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Chronic kidney disease (CKD) is a public health problem largely caused by diabetes. The epidemiology of diabetes mellitus-related CKD (CKD-DM) could provide specific support to lessen global, regional, and national CKD burden.
Data were derived from the GBD 2019 study, including four measures and age-standardized rates (ASRs). Estimated annual percentage changes and 95% CIs
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Ratiometric near-infrared fluorescent probes (AH+ and BH+) have been prepared for pH determination in mitochondria by attaching dithioacetal and formal residues onto a hemicyanine dye. The reactive formyl group on probe BH+ allows for retention inside mitochondria as it can react with a protein primary amine residue to form an imine under slightly basic pH 8.0. Probes AH+ and BH+ display ratiometric fluorescent responses to pH changes
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Radiomics transforms the medical images into high-dimensional quantitative features and provides potential information about tumor phenotypes and heterogeneity. We conducted a retrospective analysis to explore and validate radiomics model based on contrast-enhanced computed tomography (CECT) to predict recurrence of locally advanced oesophageal squamous cell cancer (SCC) within 2 years after trimodal therapy. This st
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OBJECTIVES To identify and characterise a subgroup of patients with early rheumatoid arthritis (RA) reporting not feeling well 1 year after treatment initiation despite achieving optimal disease control according to current treatment standards. METHODS This observational study included participants of the Care in early RA trial with a rapid and sustained response (DAS28CRP less then 2.6) from week 16 until year 1 after
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The response to treatment appears to be better among pediatric patients. We aim to review FMDs in children to better understand the different aspects of their frequency, clinical features, precipitating factors, diagnosis, treatment, and outcome.Managing the heterogeneity of Parkinson’s disease symptoms and its progressive nature demands strategies targeting the hallmark disrupted neurotransmission but also the como
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as no significant relationship between knowledge and number of years working in the surgical ward (r = 0.06, p=0.36). Also, there was no significant relationship between nurses’ knowledge and nurses’ attitude (r = 0.06, p=0.36). Conclusion and recommendation. The level of knowledge and attitude towards postoperative management were generally inadequate among nurses. Therefore, there is the need to implement in-service train
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To explore contractile actions of angiotensin II (ATII) on the muscularis mucosae (MM) of the bladder, ATII-induced contractions were compared between MM and the detrusor smooth muscle (DSM) of the pig bladder by isometric tension recordings. Effects of ATII on spontaneous Ca2+ transients in MM were visualized using Cal-520 fluorescence. ATII receptor type 1 (ATR1) expression in MM and DSM was also exa
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The three groups did not differ on neuropsychological variables except for TBPM where TD-PD and CD patients performed worse than HCs; moreover, TD-PD performed worse than CD patients. Moderation analysis indicated that the type of movement disorder moderated the relationship between executive dysfunction and TBPM, but not EBPM. In conclusion, selective deficit of TBPM characterizes both CD and TD-PD but it is associated with
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OUTCOMES Participants slept on average 6.4 h per night, with 62% indicating great rest quality. Stress had significant, positive interactions with exhaustion, cynicism, and inefficacy. The connection between anxiety and exhaustion lessened as sleep duration increased, and the commitment between tension and fatigue was weaker among pupils w
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This approach provided an optimal implant placement accuracy reducing surgical invasiveness.This study aimed to determine whether isotopic ratio mass spectrometry (IRMS) can discriminate farmed European sea bass according to different farming systems and geographic origins. Dicentrarchus labrax of commercial size from three different rearing systems (concrete tank inland, sea cages, and extensive method
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Uncontrolled type 1 diabetes mellitus (T1D) impairs reproductive potential of males. Insulin treatment restores metabolic parameters but it is unclear how it protects male reproductive health. Herein, we hypothesized that insulin treatment to T1D rats protects testicular physiology by mediating mechanisms associated with ap
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Among the samples obtained, APS-II showed the best effects. Compared with those in the blank group, 29 metabolites determined by UHPLC Q-Exactive MS in the serum of the model group changed remarkably, and APS-I, APS-II, and APS-III respectively restored 13, 25, and 19 of these metabolites to normal levels. Metabolomics analysis revealed that APS-II is mainly responsible for the immunomodulatory activity of APS
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Relative control of HIV-1 infection has been linked to genetic and immune host factors. In this study, we analyzed 96 plasma proteome arrays from chronic untreated HIV-1-infected individuals using the classificatory random forest approach to discriminate between uncontrolled disease (plasma viral load [pVL] >50,000 RNA copies/ml; CD4 counts 283 cells/mm3, n = 47) and relatively controlled disease (pVL less the
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Such models have, relatively rapidly, been validated and are now receiving approval from health regulation authorities with deployment into the clinical sphere. In this review, we chart the evolution of global DR screening programmes since their inception highlighting major milestones in healthcare infrastructure, telemedicine approaches and imaging devices that have shaped the robust and
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Biomolecular hydration is fundamental to biological functions. Using phase-resolved chiral sum-frequency generation spectroscopy (SFG), we probe molecular architectures and interactions of water molecules around a self-assembling antiparallel β-sheet protein. We find that the phase of the chiroptical response from the O-H stretching vibrational modes of water flips with the absolute chirality of the (l-) or (d-) antipar
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ecover from these disturbances. To address this important question, we investigated growth disruption resilience in the model bacterium Escherichia coli and its dependence on the stringent response alarmone (p)ppGpp by quantifying ppGpp and pppGpp levels as growth was disrupted and then recovered. Our findings may thus contribute to understanding how ppGpp improves E. coli’s resilience to nutritional stress and other e
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The main functions of automotive suspensions are to improve passenger comfort as well as vehicle dynamic performance. Simultaneously satisfying these functions is not possible because they require opposing suspension adjustments. This fundamental design trade-off can be solved with an active suspension system providing real-time modifications of the suspension behavior and vehicle attitude correctio
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This paper analyzes the way in which the EFSA has addressed the limitations that the essentiality of nutrients presents to the requirement of obtaining evidence from RCTs for the scientific substantiation of health claims. By redefining the requirements to affirm causality in the case of essentiality of nutrients, the EFSA has constrained the debate on the relevance of different methodologies in the field of nutrition
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Regarding CCS severity, sCD40L levels showed a significant stepwise increase with increasing angina severity (ANOVA P=0.001). In addition, sCD40L was independently associated with the anatomical severity of coronary artery disease, as assessed by the Gensini score. Among patients with CCS, those with previous coronary artery bypass grafting (n=23) had lower sCD40L levels than patients waiting for revascularization (n=45) [4
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In addition, knockdown of the vitamin D receptor (VDR) abolished the radiosensitization of 1α,25(OH)2D3, which confirmed that 1α,25(OH)2D3 radiosensitized tumor cells that depend on VDR. Similarly, our study also evidenced that vitamin D3 enhanced the radiosensitivity of cancer cells in vivo and extended the overall survival of mice with tumors. In summary, these results demonstrate that 1α,25(OH)2D3 enhances the rad
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The Senegal National Malaria Control Programme (NMCP) introduced home-based malaria management for all ages, with diagnosis by rapid diagnostic test (RDT) and treatment with artemisinin-based combination therapy (ACT) in 2008, expanding to over 2000 villages nationwide by 2014. With prise en charge à domicile (PECADOM), community health workers (CHWs) were available for community members to seek care, but did not ac
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In his serially published atlas of pathology, Anatomie Pathologique du Corps Humain (1829-1842), French anatomist and pathologist Jean Cruveilhier (1791-1874) provided an early clinical-pathologic description of Dyke-Davidoff-Masson syndrome. Cruveilhier’s case was initially published around 1830, more than a century before the clinical and radiologic report of Dyke and colleagues in 1933 based on a serie
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More robust studies are needed to determine the safety and feasibility of applying low-risk guidelines to this patient population to reduce practice variability and eliminate unnecessary laboratory evaluation and monitoring.
In otherwise healthy hospitalized patients less then 3 years of age with a primary diagnosis of FTT, routine laboratory monitoring for electrolyte derangem
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The Ministry of Health in Québec requested the National Institute of Excellence in Health and Social Services to produce clinical and implementation recommendations for the prophylaxis, diagnosis, and treatment of Lyme disease.
(i) Describe the process of trialing different modalities of patient engagement as a means to integrate a diversity of patient perspectives and (ii) D
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Finally, we present the challenges and perspectives for multi-omics development.Convulsive status epilepticus is the most serious manifestation of an epileptic diathesis. In the early stages (5-30 min), there exists class A evidence to support the efficacy of benzodiazepines as first-line treatment. As status epilepticus progresses into the later stages, the evidence for treatment becomes less robust until we are depending u
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N9-GP produced the highest median in vivo recovery value (1.70 IU/dL per IU/kg) compared with 1.18, 1.00, and 1.05 IU/dL per IU/kg for rIX-FP, rFIXFc, and rFIX, respectively.
When comparing EHL products, not only half-life but also exposure must be considered. In addition, variation in extravascular distribution of the FIX concentr
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One hundred sixty-two consecutive patients undergoing lumbosacral transforaminal epidural treatments from February 2018 to Summer 2019 had been recruited and randomized to every supply for the ) respectively [p = 0.375]. The analysis showed no statistically considerable difference in intravascular uptake or pain perception between a 22-gauge needle and 25-gauge needle during lumb
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In the subgroup analyses, people with the coexistence of high depressive symptom burden and hypertension had the highest risk of new-onset stroke in all subgroups.
Our results suggest a combined effect of high depressive symptom burden and hypertension on stroke risk among the middle-aged and elderly Chinese.
Our results suggest a combined effect of
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CONCLUSIONS Ig replacement therapy or prophylactic antibiotics for MM patients with SID were lacking in this single retrospective study. IgG less then 5 g/L could be a prognostic marker for MM patients.
Preclinical studies have reported significant changes in the gut microbiome after traumatic brain injury (TBI). We hypothesized that TBI induces the growth of Proteobact
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The tumor suppressor protein p53 is a critical hub in the comprehensive transcriptional network that inhibits the growth of cells after acute stress stimulation. In this paper, an integrated model of the p53 signaling pathway in response to DNA damage is proposed and the p53 stability and oscillatory dynamics are analyzed. Through theoretical analysis and numerical simulation, we find that the delay as a bifurc
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24, p less then 0.001). In all three disease subtypes, patients in CR at allo-HSCT tended to have a lower cumulative incidence of relapse than did those in non-CR (T-ALL 13.6 % vs. 50.0 %, p = 0.10; T-LBL 20.0 % vs. 50.0 %, p = 0.21; B-ALL 10.0 % vs. 56.0 %, p less then 0.01). Thus, the outcomes of allo-HSCT for T-ALL/LBL were comparable to those of Ph-negative B-ALL. Irrespective of the disease subtypes, ach
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The three markers correlated with each other, tau isoforms, age, and those inflammatory markers previously described as related to neurodegeneration, predominantly sTREM2, macrophage migration inhibitory factor, soluble vascular endothelial growth factor receptor, soluble vascular cell adhesion molecule 1 (sVCAM-1), and C1q. These interrelations existed in subjects with pathological and sub-pathological t
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The results show that our proposal can significantly improve the network performance when ahandover happens. Human α-calcitonin gene-related peptide (h-α-CGRP) is a highly potent vasodilator peptide that belongs to the family of calcitonin peptides. There are two forms of CGRP receptors in humans and rodents α-CGRP receptor predominately found in the cardiovascular system and β-CGRP receptor predominating in the gastroi