Burnie Burns, born as Michael Justin Burns, is the CEO of RoosterTeeth and the creator of Red v. Blue and Lazer Team, along with other projects created under RoosterTeeth. Burnie was born in New York, but has lived most of his life in Austin, Texas, where RoosterTeeth is currently located.
In his early life, he went to Alief Elsik High School, where he got the nickname “Burnie.” It was given to him by a classmate who wanted to differentiate him between the other Michael’s in his class. He then went on to go to The University of Texas at Austin. Here, he started working on the campus TV station. While he was there, he started a new TV program Sneak Peak, which is the longest running student television show at The University of Texas at Austin.
While attending school, he was working at a tech company where he met future co-founders of RoosterTeeth, Geoff Ramsey and Gus Sorola. As they started working together, they started to develop a new, game changing video-game based videos. The videos were called Red v. Blue. They used a technique called machinima, which means to take pre-recorded game play from a video game and dub audio over top to make create a story. When they first used this technique, it was widely disregarded, and nobody really paid any attention to the series. After they got recognition from Computer Gaming World, the series became so popular, that they had to revise their original thought of only making these short, comedic videos to a full season length, consisting of 20 episodes or so per season.
Because of the popularity they were getting, the decided to make their own website, properly named redvblue.com. Their domain name has since changed to RoosterTeeth.com, because after Red v. Blue, their company grew beyond their imaginations. Over the course of the next couple of years, they went on to make more machinima content, like The Strangerhood and PANICS. These shows made their popularity grow even more, so Burnie had to grow his company.
Presently, they have made a lot of great content. To name some, Immersion, where they take video game situations and try to replicate them in real life, RWBY, being a very popular anime show, and The RoosterTeeth Podcast, where his co-founder, Gus Sorola, hosts a podcast every week and has guests through out the company talk about recent events and popular topics.
Because of them, they have inspired me to pursue the Communication Media field so i can one day hopefully work for them. To hear their story, to have them come up from nothing and create such a successful company, who has produced a Blockbuster movie called Lazer Team, it has motivated me to learn all i can about production and editing.
Have you ever heard of these guys? Do you love them as much as i do? Let me know in the comments below about what you think!
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Using an On-Demand panel, we identified 18 pathogenic mutation carriers, seven of which would have gone unnoticed with traditional analysis. Conclusions Our results reinforce the utility of NGS gene panels in the diagnostic routine to increase the performance of genetic testing, especially in individuals from families with overlapping cancer phenotypes.Background Cardiovascular outcome trials in high-risk pat
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The existence of taste and odour (T&O) in drinking water is one of the principal causes of consumer complaints and is commonly related to algae growth. Numerous studies have confirmed the existence of algal blooms emerging specifically in low-temperature periods, herein referred to as “cold algae”; these include chrysophytes, cryptophytes, dinoflagellates and diatoms. In addition, the adaption mechanisms of
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The maximum thermal energy and exergy allow the normalization of the first and second laws of thermal efficiencies. These evaluation methods can be applied to optimized OTEC systems and their effectiveness is confirmed.Transport phenomena are ubiquitous in physics, and it is generally understood that the environmental disorder and noise deterior
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The flexible control of sequential behavior is a fundamental aspect of speech, enabling endless reordering of a limited set of learned vocal elements (syllables or words). Songbirds are phylogenetically distant from humans but share both the capacity for vocal learning and neural circuitry for vocal control that includes direct pallial-brainstem projections. Based on these similarities, we hypothesized that
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In this study, a novel at-line nanofractionation screening platform was successfully developed for the rapid screening and identification of α-glucosidase inhibitors from natural products. A time-course bioassay based on high density well-plates was performed in parallel with high resolution mass spectrometry (MS), providing a straightforward and rapid procedure to simultaneously obtain chemical and biological info
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Thirteen patients (52%) were treated conservatively with analgesia. Surgical decompression was performed in 10 patients (40%). At the final follow-up, complete resolution of symptoms was achieved in 12 patients (48%). Conclusions Although rare, iliacus hematoma syndrome carries significant morbidity. Spontaneous iliacus muscle hematoma should be considered in the differential dia
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In our previous study, we observed that androgen deprivation therapy (ADT) may induce a compensatory increase in MAPK or JNK signaling. Here, we tested the effects of the MEK inhibitors PD0325901 and GSK1120212, ERK1/2 inhibitor GDC-0994, and the JNK inhibitor AS602801 alone and in combination with the AR inhibitor enzalutamide (ENZ) in androgen-sensitive LNCaP cells and androgen-resistant C4-2 and 22Rv1 cell
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In summary, our observations provide insight into the dengue-induced inflammatory response mechanism and highlight the importance of DENV-2 NS2A and NS2B proteins in activation of the NLRP3 inflammasome during dengue virus infection. Copyright © 2020 Shrivastava, Visoso-Carvajal, Garcia-Cordero, Leon-Juarez, Chavez-Munguia, Lopez, Nava, Villegas-Sepulveda and Cedillo-Barron.The axonal guidance molecules, semaph
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Purpose Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly. The role of systemic inflammation in AMD remains unclear specifically in patients with intermediate AMD (iAMD). We sought to determine whether systemic inflammation was associated with future iAMD progression.Methods Combinations of 27 circulating inflammatory markers including complement factors, cytokines, chemokines, and high-s
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The hydrogels were then exposed to a fatigue test under physiological pulsatile flow, inducing a combination of circumferential and shear stresses. The hydrogels withstood 5.5 million cycles and no significant weight loss of the implant was observed nor did the polymerized hydrogel protrude or migrate into the parent artery. Slight surface erosion defects of 2-10 μm in depth were observed after loading compared to 2 μ
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These lactate dependent effects on stemness properties are abrogated by the MCT1/lactate-uptake inhibitor 7ACC2 or MCT1 knock-down. Furthermore, the clinical relevance of these observations was supported by detecting co-expression of MCT1 and reprogramming factors in human PDAC tissues. In conclusion, the MCT1-dependent import of lactate supplies “reverse Warburg “PDAC cells with an efficient driver of meta
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05). Dietary L. acidophilus supplementation consistently showed higher BW, ADG, ADFI, and jejunum and ileum VC ratio at 14 d and 21 d in the presence and absence of E. coli challenge (P less then 0.05). L. acidophilus supplementation reduced the mortality rate caused by E. coli challenge (P less then 0.05), decreased the serum CRP, DAO, and LPS levels at 14 d and 21 d; upregulated the mRNA expression o
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Although long-term care (LTC) home staff of nurses and personal support workers spend the most time providing direct care, their role in end of life decision-making for residents with dementia has largely been unacknowledged. Staff’s perceptions of their role play a significant part in how they support people with dementia and family care partners. The purpose of this study was to examine LTC home staff’s
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Hemoglobin (Hb)-F inducers are known to improve Hb level and transfusion dependence in thalassemia. This pilot study was conducted to assess the efficacy and safety of Hb-F inducer thalidomide compared to hydroxyurea (HU) in Hb E-β thalassemia patients.
This was a prospective interventional single-centre study with 45 Hb E-beta thalassemia patients equally divided into group-
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Publications of Phase 3, randomized, blinded, for-profit-company supported/sponsored, multi-center trials, and trials with a larger number of subjects were shown to have a higher scientific impact. Publications of clinical trials of newly developed molecular target drugs, including epidermal growth factor receptor-tyrosine kinase inhibitors, anaplastic lymphoma kinase inhibitors, and immune checkpoint inhibitors demonstrated a hig
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Our assays are rapid, inexpensive, high capacity, easy to perform, and only require small sample amounts. Therefore, they facilitate the breeding and study of KS mouse models and help advance our knowledge of the pathological mechanism underlying KS.Patients with chronic liver disease (CLD) and liver transplant recipients are at increased risk of morbidity and mortality from coronavirus disease 2019 (COVID-19). A
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he RIC Flu/TBI platform for lymphomas. Allogeneic stem cell transplantation is applied to patients suffering from hematological malignancies to replace the diseased hematopoietic system with cells derived from a donor stem cell graft. The majority of 10/10 matched unrelated donors are HLA-DP-mismatched and this may result in varying degrees of graft-versus-leukemia (GVL) effect with or without the
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Among them was Staphylococcus epidermidis, an anaerobic staphylococcus that was shown to contribute to the suppression/manipulation of phytohormone-dependent plant defense signaling. The presence of OS bacteria was consequently beneficial for S. litura larvae hosted by Brassicaceae.
To evaluate in a laboratory setting the influence of several model system parameters on the sodium hypochlorite (NaOCl) susceptibility of e
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Trypanosoma cruzi is a protozoan parasite that infects at least 7 million persons in the world (OMS, 2019). In endemic areas, infection normally occurs by vectorial transmission; however, outside, it normally happens by blood and includes congenital transmission. The persistence of T. cruzi during infection suggests the presence of immune evasion mechanisms and the modulation of the anti-parasite response to a pr
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The results showed that the combined therapy had superior renoprotective effect as evident by significant improvement in kidney function and renal architecture changes through rebalancing of inflammatory, fibrotic and apoptotic markers. Based on these outcomes, ADMSCs with exenatide were supposed to effectively ameliorate diabetic renal dysfunction compared to ADMSCs solely, presenting a promise t
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The aim of this work is to simulate with high accuracy an episode of high NO2 pollution during December 2016 in the city of Madrid (Spain). For this purpose, a multiscale modelling system has been implemented that includes a mesoscale model (WRF/Chem) up to a horizontal resolution of 1 km and a computational fluid dynamics model (CFD; MICROSYS) with a resolution of 5 m. For the calculation of
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Higher ALT levels might impair the accuracy of AFP for diagnosing HCC. AFP tests showed better accuracy in patients with ALT ≤ 2 ULN whereas the AFP/(ALT × AST) ratio was recommended in patients with elevated ALT levels.
Higher ALT levels might impair the accuracy of AFP for diagnosing HCC. AFP tests showed better accuracy in patients with ALT ≤ 2
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เครดิตฟรีสล็อต เป็นแบบความรื่นเริงใจด้านการเดิมพันยอดนิยม จากเครื่องสล็อตแบบเริ่ ั่งวิดีโอสล็อตยุคใหม่ เกมพวกนี้มีการปรับปรุงโดยตลอดและก็ยั่วยวนใจผู้เล่นจากทั่วทุกมุมโลก ด้วยความรุ่งเรืองของเทคโนโลยี การเปิดตัว สล็อตที่เยี่ยมที่สุดจัดหนักจัดเต็ม ได้นำเกมคาสิโนคลาสสิกนี้ไปสู่อีกระดับหนึ่ง ในเนื้อหานี้ พวกเราจะมาดูประวัติความเป็นมาของสล็อตออนไลน์อย่างละเอียดเพิ่มขึ้น แล้วก็แนวทางที่สล็อตกลุ่มนี้แปลงเป็นตัวเลือกที่สบายและก
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The recent discovery that an ERK signaling modulator [ACA-28 (2a)] preferentially kills human melanoma cell lines by inducing ERK-dependent apoptosis has generated significant interest in the field of anti-cancer therapy. In the first SAR study on 2a, here, we successfully developed candidates (2b, 2c) both of which induce more potent and selective apoptosis towards ERK-active melanoma cells than 2a, thus revealing the struc
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Therefore, CSA-C8 and CSA-S50 improved the detection e
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Het buitendeel wordt meestal op een platdak, aan de muur of in de tuin geplaatst. Een schaduwrijke plaats die vrij is van obstakels biedt het . Verduurzamen heeft tot gevolg dat er vele mensen hun woning beter gaan isoleren. In de winter blijft de warmte hierdoor beter binnen en tijdens de zomermaanden houdt het de warmte juist beter buiten. Mechanische ventilatie of
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Despite the wide demand for thin flaps for various types of extremity reconstruction, the thin elevation technique for anterolateral thigh (ALT) flaps is not very popular because of its technical difficulty and safety concerns. This study proposes a novel perforatorcentralizing technique for super-thin ALT flaps and analyzes its effects in comparison with a skewed-perforator
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Individuals with the highest quartile of VO2max/kg had 23-fold lower miR-126 expression in comparison to subgroups with lower VO2max/kg (p = 0.017). Our results may indicate that both miRNAs may serve as a biomarker for early pathological changes leading to atherosclerosis burden in athletes. Furthermore, the association between miRNAs and traditional risk factors for CVD indicate a possible use of these molecu
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This is of interest in order to face not only acute respiratory-related coronavirus (SARS-CoV) responsible for the COVID-19 pandemic but also for future virus infection challenges.Regular exercise during school hours is encouraged since childhood obesity has reached epidemic proportions. Moreover, a great majority of adolescents do not meet the recommendations for moderate-to-vigorous physical activity. The present study ai
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The results implied that modulation of QS in denitrifying bacteria, possibly through quorum quenching or QS inhibition, could help to improve the reduction of nitrate in wastewater treatment.The residue of organochlorine pesticides (OCPs) has been a major pollution problem in our environment. Dichlorodiphenyltrichloroethane (DDT) is one of the most common persistent OCPs that continue to pose a serious risk to human health
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After several seconds of adaptation to a visual array of randomly oriented Gabor patterns, observers can detect and localise a change in the orientation of one of these Gabors, even when the change is preceded by a blank inter-stimulus interval. Previously, we reported that the ability to detect this changed element was unaffected by distracting observers’ attention away from the adapting stimuli by making
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Enteric pathogen-host interactions occur at multiple interfaces, including the intestinal epithelium and deeper organs of the immune system. Microbial ligands and activities are detected by host sensors that elicit a range of immune responses. Membrane-bound toll-like receptors and cytosolic inflammasome pathways are key signal transducers that trigger the production of pro-inflammatory molecules, such as cytokines and
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90 and test-retest reliability of 0.56 after 3 weeks. The best cutoff point for this questionnaire (MPA) was 46. Also, 4 factors were extracted by principal components method and varimax rotation “excessive use of cell phone,” “addictive use of social networks,” “mood modification,” and “preoccupation” for both male and female students. Conclusion MPA could be used in studies on the evaluation of mobile phone addiction. Th
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This study evaluated changes in nasal airway function following Le Fort I osteotomy with maxillary impaction according to the Nasal Obstruction Symptom Evaluation (NOSE) scale.
This cohort study included 13 patients who underwent Le Fort I osteotomy with maxillary impaction. Nasal airway function
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Nationally, for the overall SVI measure, vaccination coverage was higher (15.8%) in low social vulnerability counties than in high social vulnerability counties (13.9%), with the largest coverage disparity in the socioeconomic status theme (2.5 percentage points higher coverage in low than in high vulnerability counties). Wide state variations in equity across SVI metrics were found. Whereas in the majority of states, vaccina
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Older adults with VI or HI in the United States perceive greater everyday discrimination than older adults with NSI, and those with DSI perceive even more discrimination than those wit
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• In silico tools can facilitate the optimization of gene- and protein-based factors.• Optimization of gene- and protein-based factors aids host-vector selection.• Statistical optimization is preferred for achieving optimal levels of process factors.BACKGROUND This study revisits the previously described technique of inverted-T skin-reducing mastectomy and dermal-muscle pocket as a single-stage breast reconstruction u
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Finally, we demonstrated that the energy harvested by the device from finger tapping at ~2 Hz can charge a capacitor with a large output power density of 0.45 W/cm3 and light up an ultraviolet (UV) light-emitting diode (LED). We also showed the device as a flexible wearable motion sensor, where different hand gestures were detected by the device with distinctive output voltage amplitudes and patterns.
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Levels of inflammatory markers were greater in those with noticeable endotoxin – whether false- or true positives. CONCLUSION BG levels increased with lowering renal purpose, becoming greatest in dialysis patients. High BG amounts had been involvin
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Asparaginyl endopeptidases (AEPs) are cysteine proteases that control a myriad of cellular functions in plants, including maturation of seed storage proteins and programmed cell death. Recently, several noteworthy AEPs have been discovered that primarily function as transpeptidases rather than hydrolases, to instead catalyse the formation of new peptide bonds. These AEPs appear to have evolved for the cyclisation of a large cla
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